Fig. 4.

Relaxation of fetal abdominal aortas in response to increasing doses of ACh; comparisons between SC-treated and control dams. A–D: arteries were precontracted with EC₈₀ dose of U46619. ACh dose-response curves were compared using two-way ANOVA followed by a Bonferroni post hoc test where appropriate. All data are means ± SE (n = number of animals). ■ denotes WT male, while ● denotes WT female, □ denotes P0 male, and ○ denotes P0 females. Fetuses were harvested from either SC-treated dams (gray) or control dams (black). Asterisks denote level of significance using Bonferroni post hoc test. **P < 0.01, ***P < 0.001.