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Pattern of expression during development compared with 2 mo
| TAC1/SP | NK-1R | Nur77 | EthD-1 | ||
|---|---|---|---|---|---|
| Midlevel | 2 mo | +/− | + | + | +/− |
| 6 mo | + | ++ | + | +/− | |
| Distal | 2 mo | +/− | +/− | + | + |
| 6 mo | ++ | + | ++ | + | |
| P = 0.04 vs. 2 mo Distal P = 0.03 vs. 6 mo Midlevel |
SP, substance P; NK-1R, neurokinin-1 receptor; EthD-1, ethidium homodimer-1. Note: +/−0–2, +2–3, ++ 4–5 positive clusters per airway cross section. qRT-PCR P values listed when significant.
