Table 3.

Lung injury score

	Lung Injury Score
	Edema fluid	Thickening of alveolar septa	Inflammatory infiltration
Saline	0.129 ± 0.177	0.055 ± 0.124	0.206 ± 0.034
ALI	1.468 ± 0.245*	1.718 ± 0.216*	1.925 ± 0.083*
ALI/siRNA Btk	0.163 ± 0.090	0.055 ± 0.056	0.277 ± 0.109
ALI/Cont siRNA	1.337 ± 0.170**	1.607 ± 0.276**	1.824 ± 0.141**
ALI/F(ab)2 only	1.640 ± 0.221§	1.742 ± 0.099§	1.728 ± 0.071§
ALI/siRNA MMP-9	0.069 ± 0.055	0.133 ± 0.194	0.230 ± 0.171

Values are means ± SD. Analysis was done for 4–5 animals per group.

^*P < 0.001 compared with Saline; ALI/siRNA Btk; ALI/siRNA MMP-9 groups of mice.

^**P < 0.001 compared with Saline; ALI/siRNA Btk; ALI/siRNA MMP-9 groups of mice.

^§P < 0.001 compared with Saline; ALI/siRNA Btk; ALI/siRNA MMP-9 groups of mice.