Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
Systematic review	2766 children, aged 6 months to 15 years 10 RCTs in this analysis	Adverse effects with amoxicillin or amoxicillin-clavulanic acid with macrolide antibiotics Absolute numbers not reported	RR 0.74 95% CI 0.60 to 0.90 P = 0.003	Small effect size	macrolide antibiotics