Table 2. Comparison of gene families between P. reichenowi CDC and P. falciparum 3D7.
| Gene family | P. reichenowi CDC | P. falciparum 3D7 |
|---|---|---|
| Erythrocyte membrane protein 1 | 103 | 103 |
| Complete genes | 64 | 63 |
| DBLα group 1 | 4 | 5 |
| DBLα group 2 | 6 | 3 |
| DBLα group 3 | 6 | 5 |
| DBLα group 4 | 41 | 35 |
| DBLα group 5 | 5 | 6 |
| DBLα group 6 | 2 | 8 |
| Pseudogenes (fragments) | 22 (37) | 34 (6) |
| Rifin | 462 | 184 |
| Complete genes* | 308 | 157 |
| Type A† | 113 | 46 |
| Type B† | 189 | 110 |
| Pseudogenes (fragments) | 49 (105) | 27 (0) |
| Stevor | 66 | 42 |
| Complete genes | 43 | 32 |
| Pseudogenes (Fragments) | 10 (13) | 10 (0) |
| Maurer’s cleft two transmembrane protein | 5 | 13 |
| Complete genes | 5 | 12 |
| Pseudogenes | 0 | 1 |
| Plasmodium-exported protein, unknown function | 201 | 210 |
| Complete genes | 162 | 175 |
| Pseudogenes (fragments) | 28 (11) | 35 (0) |
| FIKK kinase | 21 | 21 |
| Complete genes | 18 | 19 |
| Pseudogenes | 3 | 2 |
| Surfin | 12 | 10 |
| Complete genes | 7 | 7 |
| Pseudogenes (fragments) | 2 (3) | 3 (0) |
| Serine repeat antigen | 8 | 9 |
DBL, Duffy-binding-like domain; Surfin, surface-associated interspersed protein.
Complete genes refers to gene predictions with full-length putative protein coding sequences; Pseudogenes contain at least one in-frame stop codon or a frameshift; and ‘Fragments’ refers to partial coding sequences truncated by a contig boundary.
*The following complete genes are neither Type A nor Type B: PRCDC_1038200 and PRCDC_0004700 in P. reichenowi, and PF3D7_0401600 in P. falciparum, respectively. A further four P. reichenowi Rifins were excluded from classification owing to sequence gaps.
†Rifins were classified into types A and B as previously described in ref. 28.