Table 1.
Baseline clinical and demographic data
| Characteristics | CSA group | TAC group | P-value |
|---|---|---|---|
| Number of patients | 114 | 119 | |
| Mean recipient age (years) ± SD | 51.7±10.9 | 52.15±9.58 | ns |
| Mean donor age (years) ± SD | 37.6±13.2 | 45.3±12.2 | <0.0001 |
| Recipient sex (m/f) | 88/26 | 88/31 | ns |
| Donor sex (m/f) | 52/62 | 36/83 | 0.016 |
| Sex mismatch (n/%) | 43/37.7 | 58/48.7 | ns |
| Diagnosis leading to HTX (patients) | |||
| DCM | 62 | 64 | ns |
| CAD | 40 | 29 | ns |
| Organic heart defect | 1 | 2 | ns |
| Lung | 1 | 0 | ns |
| Other | 3 | 4 | ns |
| Cardiac amyloidosis | 7 | 20 | 0.0110 |
| Ischemic time (min) ± SD | 203.2±55.2 | 247.0±52.2 | <0.0001 |
| Change of HTX center (n) | 3 | 0 | ns |
Abbreviations: CAD, coronary artery disease; CSA, cyclosporine A; DCM, dilated cardiomyopathy; HTX, heart transplantation; m/f, male/female; ns, not statistically significant; SD, standard deviation; TAC, tacrolimus.