Table 3.
Physical evaluation of the floating gastroretentive matrix tablets of famotidine, prepared using salep
Formulation | Weight variation (mg) | Hardness (N) | Thickness (mm) | Diameter (mm) | Friability (%) |
---|---|---|---|---|---|
S1 | 270.98±1.13 | 171±4.00 | 2.31±0.14 | 9.88±0.01 | 0.49 |
S2 | 290.4±0.91 | 149±4.73 | 2.51±0.01 | 9.88±0.01 | 0.34 |
S3 | 310.9±1.06 | 124±5.77 | 2.7±0.11 | 9.87±0.02 | 0.28 |
S4 | 329.8±1.02 | 118±7.55 | 2.91±0.03 | 9.88±0.02 | 0.44 |
S5 | 351±1.06 | 99±3.61 | 3.44±0.03 | 9.88±0.01 | 0.38 |
S6 | 370.8±0.81 | 118±5.09 | 3.53±0.21 | 9.87±0.02 | 0.39 |
S7 | 390.96±1.09 | 112±4.54 | 3.77±0.09 | 9.87±0.04 | 0.24 |
S8 | 409.2±1.08 | 109±4.99 | 3.91±0.34 | 9.88±0.01 | 0.28 |
S9 | 430.57±0.98 | 108±5.45 | 3.98±0.09 | 9.88±0.02 | 0.43 |
S10 | 451±1.2 | 102±6.08 | 4.13±0.83 | 9.89±0.01 | 0.39 |
Note: Results except for friability are shown as mean ± standard deviation.