Figure 4.
Cytotoxicity assay and acute toxicity of NIR-27 in rats.
Notes: (A) The viability of A549, HBE, HepG2, and LO2 cells cultured with NIR-27 in comparison with ICG at the same dose. The data are presented as the mean ± SD (n=6). (B) Histological studies on the major organs of the NIR-27 injected mice after 7days.
Abbreviations: HBE, human bronchial epithelial cells; ICG, indocyanine green; NIR-27, heptamethine indocyanine dye; SD, standard deviation.