Table 1 Validated risk factor single nucleotide polymorphisms (SNPs) for sporadic breast cancer.
| SNP | Gene symbol | MAF | OR* | Reference |
|---|---|---|---|---|
| MAF: major allele frequency; OR: odds ratio; * all p values < 10−5. | ||||
| rs17468277 | (merged with rs1045485 G > C) CASP8/ALS2CR12; 2q33-q34 | 0.13 | 0.88 | 24 |
| rs1982073 | TGFB1 L10P | 0,45 | 1.08 | 23 |
| rs2981582 | FGFR2/LOC100131885; 10q26 | 0.38 | 1.26 | 18 |
| rs13281615 | Intergenic, FAM84B/c-MYC; 8q24 | 0.40 | 1.08 | 18 |
| rs3817198 | LSP1/H19; 11p15 | 0.30 | 1.07 | 18 |
| rs889312 | MAP3K1/MGC33648/MIER3; 5q11 | 0.28 | 1.13 | 18 |
| rs3803662 | TNRC9/TOX3/LOC643714; 16q12 | 0.25 | 1.20 | 18 |
| rs13387042 | Intergenic 2q35/TNP1/IGFBP5/IGFBP2/TNS1 | 0.52 | 1.12 | 21 |
| rs4973768 | SLC4A7/NEK10; 3p24 | 0.46 | 1.11 | 19 |
| rs6504950 | STXBP4/COX11/TOM1L1; 17q23 | 0.27 | 0.95 | 19 |
| rs10941679 | 5p12 | 0.26 | 1.19 | 20 |