Risk factor | NCI model | Claus model | BRCAPro | Tyrer et al. | BOADICEA | Tice et al. |
---|---|---|---|---|---|---|
Reference | 83, 84 | 85 | 76, 77, 78 | 81 | 79, 80, 82 | 86 |
BMI: body mass index; BOADICEA: Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm; HRT: hormone replacement therapy; NCI: National Cancer Institute. | ||||||
Age | + | + | + | + | + | + |
Age at menarche | + | + | ||||
Age at menopause | + | |||||
BMI | + | |||||
Age at first birth | + | + | ||||
History of breast biopsies | + | + | + | |||
History of premalignant lesions | + | + | ||||
HRT | + | |||||
Family history of breast cancer | + | + | + | + | + | |
Family history of ovarian cancer | + | + | + | |||
Family history of other cancers | + | |||||
Contralateral breast cancer | + | + | + | |||
Male breast cancer | + | |||||
BRCA mutation | (+) | + | ||||
Ethnicity | + | + | ||||
Mammographic density | + |