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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Eur J Epidemiol. 2010 Sep 30;25(12):855–865. doi: 10.1007/s10654-010-9512-y

Table 1.

Empirical powers of the proposed model (2.2) and the marginal model with the exchangeable (M-E) or independent (M-I) correlation structure in detecting the significant association of FPG with each of its risk factors/covariates after adjusting for the other risk factors/covariates in the model at two different significance levels (type 1 error rates) based on the 1,000 simulated data sets generated by using two different correlation matrixes R1 and R2

Correlation matrix Risk factor/covariate Significance level α = 0.05 Significance level α = 0.01


Model (2.2) M-E M-I Model (2.2) M-E M-I
R1 Age (year) 0.806 0.799 0.752 0.622 0.595 0.533
Waist (cm) 0.611 0.598 0.556 0.392 0.373 0.318
BMI (kg/m2) 0.461 0.446 0.409 0.254 0.250 0.212
Log(TG) (mg/dL) 0.994 0.992 0.989 0.982 0.969 0.967
Log(UACR) 1.000 0.999 0.999 0.999 0.999 0.999
LDL (mg/dL) 0.282 0.272 0.237 0.113 0.115 0.098
Log(Insulin) (µU/mL) 0.379 0.389 0.342 0.173 0.184 0.144
R2 Age (year) 0.946 0.849 0.776 0.815 0.662 0.541
Waist (cm) 0.770 0.612 0.529 0.535 0.365 0.297
BMI (kg/m2) 0.581 0.443 0.388 0.344 0.253 0.182
Log(TG) (mg/dL) 1.000 0.996 0.986 0.997 0.969 0.946
Log(UACR) 1.000 1.000 1.000 1.000 1.000 0.999
LDL (mg/dL) 0.392 0.311 0.242 0.165 0.139 0.101
Log(Insulin) (µU/mL) 0.565 0.443 0.369 0.346 0.224 0.166

BMI body mass index, LDL low density lipoprotein, TG triglycerides, UACR urinary albumin and creatinine ratio, Waist waist circumference