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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Pediatr Res. 2014 Apr 8;76(1):46–53. doi: 10.1038/pr.2014.53

Figure 1.

Figure 1

Hypoxic-ischemic brain injury scores. Filled circles represent brains with HI alone and open circles represent brains with HPc prior to HI. Solid horizontal line represents median score of mice receiving HI alone and dashed line represents median score of mice receiving HPc prior to HI. (a) Overall score (range 0–24). HPc protected the wildtype brain from subsequent HI. Wildtype-HI (median = 14, range 2–24) vs. wildtype-HPc/HI (median = 5, range 2–20), p=0.01. (b) Cortex (range 0–9). Wildtype-HI (median = 6 range 2–9) vs. wildtype-HPc/HI (median = 3 range 1–9) p=0.01. (c) Hippocampus (range 0–12). Wildtype-HI (median = 7 range 0–12) vs wildtype-HPc/HI (median = 2 range 0–10) p=0.001. The HIF-1α knockout brain was not protected by HPc. (a) HIF-1α knockout-HI (median = 17, range 3–24) vs HIF-1α knockout-HPc/HI (median = 16, range 5–24). (b) HIF-1α knockout-HI vs HIF-1α knockout-HPc/HI (both: median = 6 range 3–9). (c) HIF-1α knockout-HI vs HIF-1α knockout-HPc/HI (both: median = 8, range 0–12).