Table 1.
Animal numbers, mortality and sex.
| aNumber of mice and mortality: n (%) | bManner of death: n (%) | cSex: n (median score) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Total | Survived | Died | HPc | w/dam | hypoxia | post-tx | Male | Female | |
| WT-HI | 67 (28) | 32 (48) | 35 (52) | NA | 6 (17) | 22 (63) | 7 (20) | 17 (12) | 15 (15) |
| WT-HPc/HI | 56 (23) | 35 (63) | 21 (37) | 1 (5) | 5 (24) | 9 (43) | 6 (29) | 16 (8) | 19 ( 6) |
| KO HI | 64 (27) | 37 (58) | 27 (42) | NA | 4 (15) | 17 (63) | 6 (22) | 12 (15) | 25 (18) |
| KO HPc/HI | 53 (22) | 33 (62) | 20 (38) | 7 (35) | 3 (15) | 5 (25) | 5 (25) | 15 (15) | 18 (17) |
| TOTAL | 240 | 137 (57) | 103 (43) | ||||||
a
Total number of mice (n) and (%) per treatment group. Total number (n) and (%) that survived to perfusion at P12 or died prior to P12.
b
Manner of death for those that died before perfusion: during HPc; with dam after surgery; during post-surgery hypoxia treatment; after all treatments.
c
Total number of male and female mouse brains per experimental group scored for degree of injury and median score for each group.