Table 3.

Tumor protein expression of Ki67, TUNEL, PTEN, pAKT, pS6, Stathmin, and AR by SPINK1 protein expression status among men treated with radical prostatectomy for prostate cancer, Physicians’ Health Study and Health Professionals Follow-up Study cohorts

Marker	No.	Range	SPINK1 − Median (IQRa)	SPINK1 + Median (IQR)	Correlation coefficient (r)b	Pc
PTEN	761	0–0.91	0.14 (0.22)	0.27 (0.35)	+0.17	<0.01
pAKT	741	0–0.73	0.02 (0.12)	0.03 (0.14)	+0.04	0.22
pS6	746	0–0.97	0.08 (0.24)	0.04 (0.16)	−0.06	0.09
Stathmin	743	0–0.82	0.01 (0.02)	0.02 (0.04)	+0.21	<0.01
AR	802	91–152	118 (11)	114 (11)	−0.10	<0.01

^aIQR: Inter-quartile range

^bSpearman Correlation Coefficient

^cP-values from Wilcoxon rank sums test