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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Brain Behav Immun. 2014 Jun 2;41:65–81. doi: 10.1016/j.bbi.2014.04.003

Figure 1.

Figure 1

Chronological overview of the experimental paradigms conducted in this study. A, Wild-type mice were sacrificed 3 and 12 weeks after CCI injury, the time points at which they suffer neuropathic pain and were spontaneously recovered from it. Behavior (allodynia, hyperalgesia, sucrose preference, body weight, physical state measurements, open field test) was performed once a week 24 hours apart in the following order: BW and PS assessment, sucrose preference test, open filed test, von Frey filament test, hot plate. B, TNFR1 knockout mice were sacrificed 3 weeks after injury. Behavior = allodynia, body weight and physical state measurements). Sucrose preference (SP) was measured on week −1, 3 and 5. BrdU was administered weekly.