Table 5.
Risk factor | Bi-variable screening Odds Ratio (95% CI) |
p | Multivariable Analysis Odds Ratio (95% CI) |
p |
---|---|---|---|---|
Deficient retro-aortic rim | 0.30 (0.09–1.06) | 0.06 | 0.28 (0.08–1.01) | 0.05 |
Age at catheterization | 0.99 (0.93–1.04) | 0.62 | ||
Age < 3 years | 0.5 (0.06–3.66) | 0.47 | ||
Height | 1.01 (0.99–1.02) | 0.48 | ||
Weight | 1.00 (0.99–1.02) | 0.61 | ||
Qp:Qs | 2.0 (1.1–3.4) | 0.02 | 2.57 (1.22–5.40) | 0.01 |
Mean PA pressure | 1.06 (0.96–1.2) | 0.27 | ||
Defect Size | ||||
Frontal | 1.1 (0.96–1.3) | 0.15 | ||
Sagittal | 1.1 (0.94–1.27) | 0.27 | ||
Defect size on balloon sizing | 1.13 (1.05–1.21) | 0.001 | ||
Septal length | ||||
Frontal | 1.06 (0.99–1.12) | 0.08 | ||
Sagittal | 1.03 (0.97–1.09) | 0.36 | ||
Ratio of defect size to septal length | 0.6 (0.00–660) | 0.9 | ||
Defect size: BSA | 0.98 (0.87–1.09) | 0.67 | ||
Defect size: weight | 0.44 (0.04–4.6) | 0.49 |
Abbreviations: BSA body surface area, CI confidence interval, Qp:Qs ratio of pulmonary to systemic blood flow
Point-estimates, confidence intervals, and p-values for bi-variable screening are summarized. Those that met screening criteria (p<0.2) are italicized and were included in an initial multivariable model. Backwards selection was used to refine the model, based on stated criteria. The resultant final model is summarized in the columns for multivariable analysis.