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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Pediatr Cardiol. 2014 May 14;35(7):1181–1190. doi: 10.1007/s00246-014-0914-6

Table 5.

Multivariate analysis of candidate risk factors for composite outcome of technical failure or early major adverse outcome

Risk factor Bi-variable screening
Odds Ratio (95% CI)
p Multivariable Analysis
Odds Ratio (95% CI)
p
Deficient retro-aortic rim 0.30 (0.09–1.06) 0.06 0.28 (0.08–1.01) 0.05
Age at catheterization 0.99 (0.93–1.04) 0.62
Age < 3 years 0.5 (0.06–3.66) 0.47
Height 1.01 (0.99–1.02) 0.48
Weight 1.00 (0.99–1.02) 0.61
Qp:Qs 2.0 (1.1–3.4) 0.02 2.57 (1.22–5.40) 0.01
Mean PA pressure 1.06 (0.96–1.2) 0.27
Defect Size
Frontal 1.1 (0.96–1.3) 0.15
 Sagittal 1.1 (0.94–1.27) 0.27
Defect size on balloon sizing 1.13 (1.05–1.21) 0.001
Septal length
Frontal 1.06 (0.99–1.12) 0.08
 Sagittal 1.03 (0.97–1.09) 0.36
Ratio of defect size to septal length 0.6 (0.00–660) 0.9
Defect size: BSA 0.98 (0.87–1.09) 0.67
Defect size: weight 0.44 (0.04–4.6) 0.49

Abbreviations: BSA body surface area, CI confidence interval, Qp:Qs ratio of pulmonary to systemic blood flow

Point-estimates, confidence intervals, and p-values for bi-variable screening are summarized. Those that met screening criteria (p<0.2) are italicized and were included in an initial multivariable model. Backwards selection was used to refine the model, based on stated criteria. The resultant final model is summarized in the columns for multivariable analysis.