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Cerebral blood flow rate (CBFR) in gerbils (n = 5/group) following either 10 min or 20 min bilateral carotid artery occlusion (47). Control gerbils are indicated by open circles. IB-MECA (0.1 mg/kg) was injected i.p. either 15 min before ischemia (acute, filled triangles) or daily for 10 days prior to ischemia, with a 24-h gap between the last injected dose and the ischemia (chronic, filled circles).
