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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2
Methods Randomised, double blind, parallel group, no obvious enriched enrolment. Initial dose titration before fixed dose (13 weeks in total)
Participants Pain persisting for at least 3 months after healing of herpes zoster skin rash, with average daily pain score of at least 40 mm/100 mm. Mean age 70 years, 54% male
Interventions Pregabalin 150 mg daily, n = 86
Pregabalin 300 mg daily, n = 89
Pregabalin 600 mg daily, n = 97
Placebo daily, n = 97
Outcomes Proportion of patients with ≥ 30% or ≥ 50% decrease in mean pain score between endpoint and baseline, and other outcomes
Notes Oxford quality score: R1, D1, W1 = 3/5
Pfizer sponsored
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Unclear Stated to be randomised
Allocation concealment? Unclear Not described
Blinding?
All outcomes
Unclear Stated to be double blind