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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2
Methods Randomised, double blind, parallel group
Participants Women undergoing laparoscopic hysterectomy. Mean age 50 years
Interventions Diazepam 10 mg, n = 30
pregabalin 150 mg, n = 30
pregabalin 300 mg, n = 30
All given 1 hour preoperatively, and 12 hours later, when placebo was given to those initially given diazepam, and pregabalin 150 mg or 300 mg to those initially given pregabalin 150 mg or 300 mg (24 hr study)
Outcomes Postoperative pain using 11-point numerical rating scale
Notes Oxford quality score: R2, D2, W1 = 5/5
HUCH-EVO Committee and Paulo Foundation sponsored
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Yes “computer generated random number table”
Allocation concealment? Yes “opaque containers”
Blinding?
All outcomes
Yes “identical capsules”