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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2
Methods Randomised, double blind, parallel group. Single oral dose
Participants Adult patients undergoing hip arthroplasty. Mean age 68 years
Interventions Pregabalin 300 mg, n = 42
Pregabalin 300 mg + dexamethasone 8 mg, n = 42
Placebo, n = 42
Outcomes 24-hour postoperative morphine consumption, with pain scores at rest and on activity
Notes Oxford quality score: R2, D2, W1 = 5/5
No pregabalin-related sponsorship mentioned
Risk of bias
Item Authors’ judgement Description
Adequate sequence generation? Yes “computer generated block randomisation”
Allocation concealment? Yes “no person was aware of assignment”
Blinding?
All outcomes
Yes “identical capsules”