Methods | Randomised, double blind, parallel group. Single oral dose | |
Participants | Adult patients undergoing hip arthroplasty. Mean age 68 years | |
Interventions | Pregabalin 300 mg, n = 42 Pregabalin 300 mg + dexamethasone 8 mg, n = 42 Placebo, n = 42 |
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Outcomes | 24-hour postoperative morphine consumption, with pain scores at rest and on activity | |
Notes | Oxford quality score: R2, D2, W1 = 5/5 No pregabalin-related sponsorship mentioned |
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Risk of bias | ||
Item | Authors’ judgement | Description |
Adequate sequence generation? | Yes | “computer generated block randomisation” |
Allocation concealment? | Yes | “no person was aware of assignment” |
Blinding? All outcomes |
Yes | “identical capsules” |