Methods	Randomised, double blind, parallel group, partial enriched enrolment. No titration (8 weeks in total)
Participants	Painful diabetic neuropathy for 1-5 years, and pain at least 40/100 mm. Mean age 60 years, 56% female, 88% white
Interventions	Pregabalin 300 mg daily, n = 76 Placebo daily, n = 70
Outcomes	Proportion of patients with ≥ 50% decrease in mean pain score between endpoint and baseline, and other outcomes
Notes	Oxford quality score: R2, D1, W1 = 4/5 Pfizer sponsored
Risk of bias
Item	Authors’ judgement	Description
Adequate sequence generation?	Yes	“randomisation schedule”
Allocation concealment?	Unclear	Not described
Blinding? All outcomes	Unclear	Not adequately described