Number of		Percent with outcome
Outcome - daily dose	Studies	Participants	Pregabalin	Placebo	Relative benefit (95% CI)	NNT (95% CI)
At least 30% pain relief
150 mg	1	263	31	27	1.1 (0.8 to 1.7)	not calculated
300 mg	4	1374	39	28	1.4 (1.2 to 1.6)	9.2 (6.3 to 17)
450 mg	4	1376	43	28	1.5 (1.3 to 1.8)	6.6 (5.0 to 9.8)
600 mg	3	1122	39	28	1.4 (1.2 to 1.6)	9.1 (6.1 to 18)
At least 50% pain relief
150 mg	1	263	13	13	1.0 (0.5 to 1.9)	not calculated
300 mg	4	1374	21	14	1.5 (1.2 to 1.9)	14 (9.0 to 33)
450 mg	4	1376	25	14	1.7 (1.4 to 2.1)	9.8 (7.0 to 16)
600 mg	3	1122	24	15	1.6 (1.3 to 2.1)	11 (7.1 to 21)
PGIC much or very much improved
150 mg	1	263	32	27	1.2 (0.8 to 1.8)	not calculated
300 mg	4	1374	36	28	1.5 (1.2 to 1.9)	11 (7.3 to 26)
450 mg	4	1376	42	28	1.5 (1.3 to 1.8)	6.8 (5.1 to 10)
600 mg	3	1122	41	28	1.5 (1.2 to 1.7)	7.7 (5.4 to 13)
PGIC very much improved
150 mg	no data
300 mg	4	1352	17	11	1.7 (1.2 to 2.9)	16 (9.9 to 37)
450 mg	4	1354	19	11	1.8 (1.4 to 2.4)	11 (7.9 to 20)
600 mg	3	1095	12	7	1.7 (1.1 to 2.4)	21 (12 to 83)
Lack of efficacy discontinuation						NNTp (95% CI)
150 mg	1	263	9	14	0.7 (0.3 to 1.3)	not calculated
300 mg	4	1374	4	10	0.4 (0.3 to 0.7)	18 (12 to 34)
450 mg	4	1376	3	10	0.3 (0.2 to 0.5)	15 (11 to 25)
600 mg	3	1122	2	9	0.3 (0.2 to 0.5)	15 (11 to 26)