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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2

Comparison 6. Participants with at least one serious adverse event.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 At least one serious adverse event 10 Risk Ratio (M-H, Fixed, 95% CI) Subtotals only
  1.1 Pregabalin 150 mg 3 542 Risk Ratio (M-H, Fixed, 95% CI) 1.03 [0.45, 2.38]
  1.2 Pregabalin 300 mg 8 1933 Risk Ratio (M-H, Fixed, 95% CI) 1.11 [0.66, 1.85]
  1.3 Pregabalin 450 mg 2 740 Risk Ratio (M-H, Fixed, 95% CI) 1.67 [0.61, 4.52]
  1.4 Pregabalin 600 mg 9 2101 Risk Ratio (M-H, Fixed, 95% CI) 1.16 [0.74, 1.83]