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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2
Number of Percent with outcome
Outcome - daily dose Studies Participants Pregabalin Placebo Relative risk (95% CI) NNH (95% CI)
At least one adverse event
150 mg 2 449 77 71 1.2 (0.97 to 1.4) not calculated
300 mg 8 2190 82 67 1.2 (1.17 to 1.29) 6.6 (5.4 to 8.7)
450 mg 4 1379 90 74 1.2 (1.15 to 1.27) 6.3 (5.1 to 8.5)
600 mg 9 2540 83 67 1.3 (1.25 to 1.37) 6.1 (5.1 to 7.7)
At least one serious adverse event
150 mg 3 542 4.1 4.0 1.0 (0.5 to 2.3) not calculated
300 mg 8 1566 3.6 2.9 1.2 (0.7 to 2.1) not calculated
450 mg 2 740 2.7 1.6 1.7 (0.6 to 4.5) not calculated
600 mg 9 2101 3.7 3.2 1.2 (0.7 to 1.8) not calculated