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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007076. doi: 10.1002/14651858.CD007076.pub2
Number of Percent with outcome
Outcome - daily dose Studies Participants Pregabalin Placebo Relative risk (95% CI) NNH (95% CI)
Somnolence
150 mg 3 527 15 7 2.2 (1.3 to 3.7) 12 (7.3 to 34)
300 mg 4 713 19 6 3.0 (2.1 to 5.3) 7.4 (5.5 to 11)
600 mg 4 732 25 6 4.4 (2.8 to 6.8) 5.2 (4.1 to 7.0)
Dizziness
150 mg 3 527 13 10 1.3 (0.8 to 2.1) not calculated
300 mg 4 713 30 9 3.2 (2.3 to 4.6) 4.7 (3.7 to 6.5)
600 mg 4 732 35 9 4.0 (2.8 to 5.7) 3.8 (3.2 to 4.9)
Adverse event discontinuation
150 mg 3 527 9 7 1.3 (0.7 to 2.3) not calculated
300 mg 4 713 17 6 2.7 (1.7 to 4.3) 9.3 (6.5 to 16)
600 mg 4 732 19 5 3.7 (2.3 to 6.0) 7.1 (5.3 to 11)