Subjective response to alcohol and placebo in Cohort 1 and Cohort 2 heavy drinkers as measured by (a) BAES Stimulation, (b) BAES Sedation, (c) DEQ Like, & (d) DEQ Want More. Alcohol significantly increased all subjective measures in both cohorts (dose × time, p’s < 0.0001 for both cohorts on stimulation, sedation, like, and want more). The data presented from Cohort 1 was previously published in King et al., (2011a).