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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Alcohol Clin Exp Res. 2013 Oct 7;38(3):844–852. doi: 10.1111/acer.12280

Table 3.

Summary of first and second cohort results based on family history of AUD

Outcome
Measure
Original Cohort
(Dose × Time × FH)
Second Cohort
(Dose × Time × FH)
Between Cohort
Comparison (Dose × Time
× FH × Cohort)
Na (FH+) F P f b N (FH+) F P f F P
BAES
Stimulation 81 (43) 0.4 0.84 0.07 83 (47) 1.0 0.41 0.11 0.5 0.77
Sedation 81 (43) 0.3 0.89 0.06 83 (47) 0.3 0.85 0.07 0.1 0.99
DEQ
Like 81 (43) 0.3 0.80 0.07 83 (47) 0.2 0.89 0.05 0.5
Want More 81 (43) 0.2 0.88 0.05 83 (47) 0.1 0.96 0.03 0.1 0.97
Salivary Cortisol 81 (43) 3.5 0.008 0.21 82 (46) 1.2 0.33 0.12 0.6 0.70
Smooth Pursuit
Gain 75 (40) 4.5 0.01 0.25 83 (47) 1.7 0.19 0.14 0.3 0.75
Pro-saccade
Latency 77 (42) 0.5 0.62 0.08 82 (47) 0.8 0.48 0.10 1.2 0.30
Velocity 77 (42) 1.9 0.16 0.16 82 (47) 0.1 0.90 0.04 0.7 0.51
Accuracy 77 (42) 2.8 0.06 0.20 82 (47) 0.3 0.78 0.06 1.9 0.15
Anti-saccade
Latency 77 (42) 0.6 0.57 0.09 79 (46) 0 0.96 0.02 0.2 0.85
Velocity 77 (42) 1.1 0.33 0.12 79 (46) 1.3 0.28 0.13 0.8 0.45
Accuracy 77 (42) 3.7 0.03 0.22 79 (46) 1.8 0.18 0.15 1.1 0.32
DSST 81 (43) 0.3 0.85 0.07 83 (47) 1.4 0.22 0.13 0.9 0.50
Pegboarda 81 (43) 0.4 0.79 0.07 83 (47) 0.9 0.48 0.11 0.3 0.91
a

Number of participants identified as either FH+ or FH−.

b

Effect size as measured by Cohen’s f