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. Author manuscript; available in PMC: 2015 Jan 22.
Published in final edited form as: Nat Commun. 2014 Jul 22;5:4416. doi: 10.1038/ncomms5416

Fig. 3. Notch rescues the capacities of dissociated luminal progenitors for unipotent differentiation and short-term self-renewal.

Fig. 3

(a–b) H&E staining and IHC analysis of K5, K8, AR and P63 in tissues regenerated from Sca-1+ and Sca-1− cells of NICDWT and PB-NICD mice. (c) Sphere-forming activity of serially-passaged luminal sphere cultures. Scale bars, 25μm (fluorescent images in a); 50μm (fluorescent images in b); 100μm (H&E images in a, b). Data represent means ± s.d. from 3 independent experiments. Statistical significance was calculated using the t-test (***: p < 0.001).