Table 5.

Summary of Changes in Serum Inhibin and Activin in Various Diseases and Conditions

Clinical Condition	Serum Inhibin A/Inhibin B	Serum Activin A/Activin B
Pregnancy
Early spontaneous abortion/pregnancy loss	Decreased
Ectopic pregnancy	Decreased
Prenatal diagnosis of fetal Down syndrome	Increased
Pre-eclampsia	Increased
Normal/preterm labor		Increased
Infertility
Declining ovarian reserve	Decreased
Impaired spermatogenesis	Decreased
Cancer
Cancer cachexia		Increased
Bone loss		Increased
Anemia		Increased
Chemotherapy
Amenorrhea in early-stage breast cancer	Decreased