. Author manuscript; available in PMC: 2014 Oct 1.

Published in final edited form as: Crit Care Med. 2014 Oct;42(10):2258–2266. doi: 10.1097/CCM.0000000000000507

Table 8.

Association between Clinical Indicators of Adherence and Discharge Glasgow Outcome Scale (GOS) score by Each Treatment Location.

Adherence Indicators Affecting Discharge GOS (Vegetative/Major vs. Baseline/Minor/Moderate Impairment	Prehospital 5 Indicators^*	Emergency Department 5 Indicators^*	Operating Room 10 Indicators^*	Intensive Care Unit 14 Indicators^*
	aRR (95% CI)	aRR(95% CI)	aRR(95% CI)	aRR(95% CI)
Maintenance of CPP > 40mmHg
Any CPP < 40mmHg			1.00 (--)	1.00 (--)
All CPP > 40 mmHg			0.57 (0.51,0.63)	0.72 (0.59, 0.87)
Neuromuscular blockade
NMB not monitored when NMB administered			1.00 (--)
NMB monitored when NMB administered			1.33 (0.93, 1.9)
No neuromuscular blockade given			1.42 (1.28, 1.58)
Hypertonic saline/Mannitol used for high ICP
High ICP and neither used			1.00 (--)
High ICP and either/both used			0.62 (0.42, 0.93)
No high ICP present			0.59 (0.41, 0.84)

See Table1 for Location specific indicators examined.

All models adjusted for age, sex, head abbreviated injury severity (AIS) score, motor Glasgow coma scale score, and maximum non-head AIS, ICU LOS.

Each location is a separate model.

--- indicates not in the model.