Table 1.
Characteristics of patients with infections or colonization due to XDR P. aeruginosa ; Bambino Gesù Children’s Hospital, 2011–2012 (N: 27)
| Bacteremia | Other infections | Colonization | Total | |
|---|---|---|---|---|
| Number of patients | 12 | 6 | 9 | 27 |
| N (%) | N (%) | N (%) | N (%) | |
| Age | ||||
| Median | 11.5 | 15 | 11 | 12 |
| Range | (2;24) | (3;27) | (1;16) | (1;27) |
| Gender | ||||
| Male | 4 (33.3%) | 2 (33.3%) | 5 (55.6%) | 11 (40.7%) |
| Female | 8 (66.7%) | 4 (66.6%) | 4 (44.4%) | 16 (59.3%) |
| Diagnosis | ||||
| Leukemia/lymphoma | 11 (91.7%) | 4 (66.6%) | 5 (55.6%) | 20 (74.1%) |
| Solid tumor | 0 | 0 | 1 (11.1%) | 1 (3.7%) |
| Marrow failure | 0 | 1 (16.6%) | 0 | 1 (3.7%) |
| Inborn error | 1 (8.3%) | 1 (16.6%) | 3 (33.3%) | 5 (18.5%) |
| Chemotherapy | ||||
| Yes | 8 (66.7%) | 1 (16.6%) | 3 (33.3%) | 12 (44.4%) |
| No | 4 (33.3%) | 5 (83.3%) | 6 (66.7%) | 15 (55.6%) |
| HSCT | ||||
| Yes | 4 (33.3%) | 1 (16.6%) | 1 (11.1%) | 6 (22.2%) |
| No | 8 (66.7%) | 5 (83.3%) | 8 (88.9%) | 21 (77.8%) |
| Neutropenia (severity) | ||||
| <100 WBC/mm 3 | 10 (83.3%) | 1 (16.6%) | 1 (11.1%) | 12 (44.4%) |
| 100-500 WBC/mm 3 | 2 (16.7%) | 0 | 0 | 2 (7.4%) |
| >500-1000 WBC/mm 3 | 0 | 0 | 1 (11.1%) | 1 (3.7%) |
| >1000 WBC/mm 3 | 0 | 5 (83.3%) | 7 (77.8%) | 12 (44.4%) |
| Outcome | ||||
| Died | 8 (66.7%) | 0 | 0 | 8 (29.6%) |
| Alive | 4 (33.3%) | 6 (100%) | 9 (100%) | 19 (70.4%) |
WBC: white blood cells; HSCT: Hematopoietic stem cell transplantation.