Table 3.
Anovulatory subjects (with and without PCOS) classified by FSHR genotypes at codon position 307 or 680
| Variable | Polymorphism at codon 307 | Polymorphism at codon 680 | ||||||
|---|---|---|---|---|---|---|---|---|
| TT (n = 131) | TA (n = 108) | AA (n = 15) | P* | NN (n = 127) | NS (n = 116) | SS (n = 11) | P* | |
| Age (range) in year | 27.0 (20–40) | 26.5 (20–40) | 28.4 (20–38) | 0.419 | 27.1 (20–40) | 26.6 (20–38) | 27.9 (21–40) | 0.639 |
| Serum hormone | ||||||||
| FSH (mIU/mL) | 5.4 ± 2.6 | 6.2 ± 2.9 | 9.2 ± 9.7 | 0.000 | 5.5 ± 2.5 | 6.5 ± 4.5 | 5.8 ± 2.7 | 0.106 |
| LH (mIU/mL) | 9.4 ± 6.2 | 12.6 ± 8.6 | 12.7 ± 6.6 | 0.003 | 9.9 ± 6.8 | 12.3 ± 8.2 | 9.2 ± 7.0 | 0.041 |
| Estradiol (pg/mL) | 92.7 ± 138.3 | 93.9 ± 106.6 | 95.3 ± 121.1 | 0.995 | 91.8 ± 137.7 | 97.6 ± 113.2 | 61.5 ± 46.7 | 0.646 |
| Prolactin (ng/mL) | 16.5 ± 10.8 | 16.4 ± 11.5 | 13.9 ± 7.4 | 0.694 | 16.5 ± 10.8 | 15.9 ± 11.1 | 17.8 ± 9.8 | 0.822 |
| ADD (ng/mL) | 2.1 ± 1.2 | 2.1 ± 1.3 | 2.4 ± 1.1 | 0.653 | 2.1 ± 1.2 | 2.1 ± 1.2 | 2.0 ± 1.5 | 0.938 |
| DHEAS (ng/mL) | 2.1 ± 1.3 | 2.2 ± 1.6 | 2.9 ± 2.3 | 0.124 | 2.1 ± 1.4 | 2.3 ± 1.7 | 1.6 ± 0.9 | 0.169 |
| 17-OHP (ng/mL) | 1.3 ± 1.4 | 1.2 ± 0.9 | 1.5 ± 0.9 | 0.680 | 1.3 ± 1.4 | 1.3 ± 0.9 | 0.9 ± 0.7 | 0.463 |
| Testosterone (ng/mL) | 0.5 ± 0.3 | 0.5 ± 0.4 | 0.5 ± 0.4 | 0.233 | 0.5 ± 0.3 | 0.6 ± 0.4 | 0.3 ± 0.2 | 0.067 |
| SHBG (nmol/L) | 52.5 ± 43.3 | 56.4 ± 41.5 | 30.7 ± 15.0 | 0.474 | 52.7 ± 42.8 | 55.5 ± 43.3 | 46.5 ± 25.6 | 0.826 |
*oneway ANOVA test.