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. 2014 Sep 16;107(6):1318–1326. doi: 10.1016/j.bpj.2014.03.053

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(A and B) Temperature dependence of the free-energy barrier for formation of (A) I₁ state ( $Δ G_{1}^{*}$ ) and (B) pore formation ( $Δ G_{3}^{*}$ ) for control vesicles (●), vesicles in the presence of VSV-TMD (○), vesicles containing 2 mol % hexadecane (▼), and vesicles containing 2 mol % hexadecane in the presence of VSV-TMD (▵).