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. Author manuscript; available in PMC: 2015 Sep 15.
Published in final edited form as: Clin Cancer Res. 2014 Jul 23;20(18):4925–4934. doi: 10.1158/1078-0432.CCR-13-2265

Figure 1. Immunohistochemical Staining for ERG/SPINK1 and FISH for ERG Rearrangement and PTEN Deletion.

Figure 1

Panel A shows a prostatic adenocarcinoma which demonstrates positive ERG immunostaining and a corresponding ERG rearrangement by FISH. The tumor is negative for SPINK1 overexpression and shows a hemizygous deletion of PTEN.

Panel B shows a prostatic adenocarcinoma which demonstrates negative ERG immunostaining and no ERG rearrangement by FISH. The tumor shows SPINK1 overexpression and no deletion of PTEN by FISH.