Table 1.
Extraction efficiency, elution efficiency, and HPLC analysis of soluble fractions of tissue homogenates at 1 h post injection of 18F-FPRGD2
Fraction | Blood | Urine | Liver | Kidney | U87MG |
---|---|---|---|---|---|
Extraction efficiency (%) | |||||
Insoluble fraction | 5.2 | ND | 23.3 | 21.8 | 24.4 |
Soluble fraction | 94.8 | ND | 76.7 | 78.2 | 75.6 |
Elution efficiency (%) | |||||
Non-retained fraction | 2.4 | 1.2 | 23.7 | 12.6 | 28.4 |
Wash water | 1.2 | 0.2 | 4.3 | 2.0 | 4.3 |
Acetonitrile eluent | 96.4 | 98.6 | 72.0 | 85.4 | 67.4 |
HPLC analysis (%) | |||||
Intact tracer | 74.2 | 99.6 | 68.8 | 97.1 | 96.6 |
ND not determined