. Author manuscript; available in PMC: 2015 Apr 1.

Published in final edited form as: Clin Lymphoma Myeloma Leuk. 2014 Jan 22;14(2):163–171. doi: 10.1016/j.clml.2013.07.009

Table 4. Multivariate analysis of factors affecting overall survival (OS) and event-free survival (EFS) among patients with complex karyotype.

Variable	OS			EFS

	Hazard ratio	95% confidence interval	P value	Hazard ratio	95% confidence interval	P value
Chromosome 17 abnormalities	1.18	0.97-1.44	0.106	1.20	0.98-1.46	0.075
Monosomal karyotype	1.60	1.26-2.04	<0.001	1.07	0.85-1.36	0.562
Performance status	1.81	1.46-2.24	<0.001	1.73	1.40-2.14	<0.001
Response to chemotherapy^*	0.44	0.36-0.54	<0.001	0.15	0.12-0.19	<0.001
White blood cell count at presentation (<10 vs >10)	1.00	1.00-1.01	0.013	1.01	1.00-1.01	<0.001
Age (<60 vs > 60)	1.02	1.01-1.02	<0.001	1.01	1.00-1.01	<0.001

Complete remission, complete remission with incomplete platelet recovery, or complete remission with incomplete hematologic recovery.