Table 3. Baseline demographic and clinical characteristics by trial participation status.
| On Assigned AP (n = 2060) | Off assigned AP per patient request (n = 94) | Withdrew consent or lost to-follow-up (n = 202) | p-value | |
|---|---|---|---|---|
|
| ||||
| Age, mean (sd) | 63 (11) | 64 (12) | 62 (11) | 0.4 |
|
| ||||
| Male gender, % | 64 | 66 | 56 | 0.08 |
|
| ||||
| Ethnicity, % | < 0.001 | |||
| White, not Hispanic | 48 | 55 | 55 | |
| Hispanic | 37 | 20 | 20 | |
| Black | 13 | 20 | 23 | |
| Other or multiracial | 2 | 4 | 2 | |
|
| ||||
| Region, % | < 0.001 | |||
| United States/Canada | 53 | 73 | 76 | |
| Mexico/Latin America | 31 | 10 | 12 | |
| Spain | 16 | 17 | 12 | |
|
| ||||
| Education, % | 0.3 | |||
| 0-4 yrs | 13 | 12 | 9 | |
| 5-8 yrs | 18 | 12 | 16 | |
| 9-12 yrs | 38 | 35 | 39 | |
| any college | 32 | 41 | 35 | |
|
| ||||
| Marital status, % | 0.07 | |||
| never married | 8 | 9 | 11 | |
| married/common law | 66 | 55 | 57 | |
| separated/divorced | 14 | 21 | 18 | |
| widowed | 12 | 15 | 14 | |
|
| ||||
| Living arrangement, % | 0.04 | |||
| alone in own home or apt | 17 | 22 | 24 | |
| with others in home or apt | 83 | 78 | 76 | |
|
| ||||
| Mild cognitive impairment, % | 43 | 50 | 50 | 0.1 |
|
| ||||
| Barthel Index ≥ 95, % | 79 | 82 | 81 | 0.6 |
|
| ||||
| Modified Rankin Score, % | 0.4 | |||
| 0 | 15 | 19 | 17 | |
| 1 | 53 | 47 | 50 | |
| 2 | 24 | 24 | 28 | |
| 3 | 8 | 10 | 5 | |
|
| ||||
| Stroke-specific Quality of Life score at 3 mo, mean (sd) (n = 2213) | 48 (9) | 47 (10) | 46 (10) | 0.002 |
|
| ||||
| Prior symptomatic small subcortical stroke or TIA, % | 14 | 10 | 19 | 0.09 |
|
| ||||
| Frailty index | ||||
| mean (sd) | 3.3 (1.2) | 3.3 (1.1) | 3.6 (1.3) | 0.008 |
| 1-2 | 25 | 21 | 20 | 0.02 |
| 3 | 33 | 41 | 29 | |
| 4 | 26 | 26 | 27 | |
| 5+ | 16 | 12 | 25 | |
|
| ||||
| # Prescription medications, mean (sd) | 3.9 (2.2) | 4.1 (2.6) | 4.7 (2.6) | < 0.001 |
| 0-2 | 29 | 24 | 28 | |
| 3-6 | 60 | 56 | 51 | |
| 7+ | 12 | 20 | 28 | < 0.001 |