Figure 5. MRI detects infective endocarditis.

Endocarditis scores (24 h after infection with 10⁵ CFU S. aureus) for the groups defined in Fig. 2. (A) Scores for mice infected with unlabeled bacteria versus sham-surgery group. (B) Scores for mice infected with labeled bacteria versus sham-surgery group. (C) Scores for infected mice (both labeled and unlabeled) versus sham-infection groups, and score for mice with versus without injection of VSOP. n represents the number of animals. As two independent sets of scores were used the number of data points per column is 2×n. Box plots show median, 25^th and 75^th percentiles and extreme values. Significant differences are indicated: * p<0.05, ** p<0.01, ns not significant.