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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Neurochem Res. 2013 May 21;38(8):1734–1741. doi: 10.1007/s11064-013-1077-1

Figure 4.

Figure 4

EtOH-induced dysregulation of Bax and Bcl-2 in motoneurons. Representative immunoblot from three independent experiment (n = 3) showed significant increase in expression of 24 and 21 kDa Bax (↑) after exposure to EtOH compared to control (equivalent to control 2 of experiment 3) (*p≤0.05). Levels of Bcl-2 (↑) were also significantly increased by EtOH (*p ≤ 0.05), resulting in unaltered Bax: Bcl2 ration upon EtOH exposure, as shown in the lower panel. Pretreatment with calpeptin failed to reduce the levels of Bax (↓) (@p ≤ 0.05) but decreased the levels of Bcl-2 (↓) (@p ≤ 0.05).