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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Neurochem Res. 2013 May 21;38(8):1734–1741. doi: 10.1007/s11064-013-1077-1

Figure 5.

Figure 5

Calpeptin mediated protection against active caspase-3 in EtOH-exposed motoneurons. Representative immunoblots and corresponding bar graphs from three independent experiment (n = 3) showed significant activation of caspase-3 (↑), increased levels of 20 kDa and 12 kDa active caspase-3 [*p ≤ 0.05, compared to control (equivalent to control 2 of experiment 3)] in EtOH exposed motoneurons. Calpeptin relatively reduced pro-caspase-3 and significantly diminished active caspase-3 fragments (↓) in motoneurons (@p ≤ 0.05, relative to EtOH). All calpeptin doses were found effective against EtOH.