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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Neurochem Res. 2013 May 21;38(8):1734–1741. doi: 10.1007/s11064-013-1077-1

Figure 7.

Figure 7

Calpeptin mediated protection against active cathepsin-D in EtOH-exposed motoneurons. Representative immunoblots from three independent experiment (n = 3) and corresponding bar graphs showed significant activation of cathepsin-D (↑), increased levels of intermediate and mature cathepsin-D [*p ≤ 0.05, compared to control(equivalent to control 2 of experiment 3)] in EtOH exposed motoneurons. Calpeptin relatively reduced pro-cathepsin-D and significantly diminished intermediate and mature fragments (↓) in motoneurons (@p ≤ 0.05, relative to EtOH). All calpeptin doses were found effective against EtOH.