Table 3. Pre- and post-treatment enamel thickness and optical reflectance intensity.

	Pre-treatment	Post-treatment	Change
	Mean measured enamel thickness at probe location ± s.e.m.
Esomeprazole, n = 167 teeth	2142.6 μm ± 0.16	2135.4 μm ± 0.16	7.2 μm ± 0.16*
Placebo, n = 193 teeth	2215.9 μm ± 0.17	2200.6 μm ± 0.17	15.3 μm ± 0.18*
	Mean measured optical intensity at probe location ± s.e.m.
Esomeprazole, n = 167 teeth	55.8879 dB ± 0.7690	54.7659 dB ± 0.7600	−1.1220 dB ± 0.7691#
Placebo, n = 193 teeth	52.2864 dB ± 0.5404	54.3454 dB ± 0.5339	+2.0590 dB ± 0.5329#

^*P = 0.013;

^#P = 0.012.