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Brain MRI. Newborn with classic adrenal congenital hyperplasia, on day 12 after birth, white matter abnormalities that consisted of bilateral small diffuse hyperintensities (white arrow) are depicted on T1-weighted images (a). At 1 yr. of age, bilateral small diffuse hyperintensities are documented (white arrow) on T1-weighted images (b). (Reprinted with permission from [49], Copyright Japanese Society for Pediatric Endocrinology).
