Table 2.
Comparison with previous work
| Study | No. of tumors | Time of PET follow-up (range) | Location of residual FDG avidity |
|---|---|---|---|
| Abramyuk et al, 2009 (16) | 10 | 8 months (6-9 months) | Small tumors (<10 cm3) - center of baseline FDG uptake Large tumors (>10 cm3)- within 35% SUVmax of baseline FDG uptake |
| Aerts et al, 2009 (9) | 22 | 3 months (49-184 days) | Overlap fraction of 50% of SUVmax of baseline FDG uptake with 80% of SUVmax of residual FDG uptake - 0.77 (95% CI: 0.66-0.88) |
| Aerts et al, 2012 (17) | 7 | 3 months | Overlap fraction of 50% of SUVmax of baseline FDG uptake with 70%-90% of SUVmax of residual FDG uptake: 67.9 ± 6.8% (range, 61.5-82.6%) |
| Present study | 17 | 10 days (10-17 days) 3 months (61-139 days) 6 months (181-212 days) |
Overlap fraction of 50% of SUVmax of baseline FDG uptake with 80% of SUVmax of residual FDG uptake 0.80 (95% CI: 0.7-0.9): 10 days after RT 0.63 (95% CI: 0.49-0.77): 3 months 0.38 (95% CI: 0.19-0.57): 6 months |
Abbreviations: FDG = 2-deoxy-2-fluoro-D-glucose; PET = positron emission tomography; RT = radiation therapy; SUVmax = maximum standard uptake value.