Methods	Allocation: random, no further details. Blindness: double, no further details. Duration: 6 weeks. Design: parallel.
Participants	Diagnosis: (DSM-IV) schizophrenia, schizophreniform disorder, schizoaffective disorder, delusional disorder or shared psychotic disorder. N = 36. Age: 65 years or more. Sex: not described. Location: not described. Setting: not described. History: duration ill, age at onset: not described. Excluded: conditions such as: not described.
Interventions	Amisulpride: flexible dose. Allowed dose range: 100-400 mg/day. Mean dose: n.i. N = 24 Risperidone: flexible dose. Allowed dose range: 1-4 mg/day. Mean dose: n.i. N = 12
Outcomes	Leaving the study early: adverse events. Cognitive functioning: MMSE. Adverse effects: open interviews. Unable to use: Mental state, PANSS total score, BPRS total score: no usable data. Cardiac effects (QTc), laboratory tests: no data.
Notes
Risk of bias
Bias	Authors’ judgement	Support for judgement
Adequate sequence generation?	Unclear risk	Random, no further details.
Allocation concealment?	Unclear risk	No further details.
Blinding? subjective outcomes	Unclear risk	Double, no further details. Whether blinding was successful has not been examined, but both compounds differ in side effects. This may be a problem for blinding
Blinding? objective outcomes	Low risk	Objective outcomes such as laboratory measures or death are unlikely to have been much affected by problems of blinding
Incomplete outcome data addressed? All outcomes	High risk	Numbers of participants leaving the study early were only reported for the category “due to adverse effects”. The statistical method used to account for incomplete data was not described
Free of selective reporting?	High risk	The study is only available as an abstract. The data for primary outcomes were either not available or only available in percentage change without a standard deviation
Free of other bias?	High risk	The study was sponsored by the manufacturer of amisulpride. Whether there was a baseline imbalance could not be judged due to insufficient data