Methods | Allocation: random, no further details. Blindness: double, no further details. Duration: 6 weeks. Design: parallel. Location: not reported. |
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Participants | Diagnosis: schizophrenia or schizoaffective disorder, first episode. N = 42. Sex: not reported. Age: not reported. History: duration ill not reported, age at onset not reported. Setting: inpatient. |
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Interventions |
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Outcomes | Mental State: PANSS total score. | |
Notes | ||
Risk of bias | ||
Bias | Authors’ judgement | Support for judgement |
Adequate sequence generation? | Unclear risk | Random, no further details. |
Allocation concealment? | Unclear risk | No further details. |
Blinding? subjective outcomes |
Unclear risk | Double, no further details. Whether blinding was successful has not been examined, but the compounds differ quite substantially in side effects. This can be a problem for blinding |
Blinding? objective outcomes |
Low risk | Objective outcomes such as laboratory measures or death are unlikely to have been much affected by problems of blinding |
Incomplete outcome data addressed? All outcomes |
High risk | Data on subjects leaving the study early were not available. |
Free of selective reporting? | High risk | Allowed study medication dose ranges were not indicated. A publication was not available |
Free of other bias? | Unclear risk | Insufficient information. |