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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Cochrane Database Syst Rev. 2011 Jan 19;(1):CD006626. doi: 10.1002/14651858.CD006626.pub2
Methods Allocation: random, no further details.
Blindness: double, no further details.
Duration: 6 weeks.
Design: parallel.
Location: not reported.
Participants Diagnosis: schizophrenia or schizoaffective disorder, first episode.
N = 42.
Sex: not reported.
Age: not reported.
History: duration ill not reported, age at onset not reported.
Setting: inpatient.
Interventions
  1. Olanzapine: fixed/flexible dose: not reported. Allowed dose range: not reported. Mean dose: not reported. N = 21.

  2. Risperidone: fixed/flexible dose: not reported. Allowed dose range: not reported. Mean dose: not reported. N = 21

Outcomes Mental State: PANSS total score.
Notes
Risk of bias
Bias Authors’ judgement Support for judgement
Adequate sequence generation? Unclear risk Random, no further details.
Allocation concealment? Unclear risk No further details.
Blinding?
subjective outcomes
Unclear risk Double, no further details. Whether blinding was successful has not been examined, but the compounds differ quite substantially in side effects. This can be a problem for blinding
Blinding?
objective outcomes
Low risk Objective outcomes such as laboratory measures or death are unlikely to have been much affected by problems of blinding
Incomplete outcome data addressed?
All outcomes
High risk Data on subjects leaving the study early were not available.
Free of selective reporting? High risk Allowed study medication dose ranges were not indicated. A publication was not available
Free of other bias? Unclear risk Insufficient information.