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. Author manuscript; available in PMC: 2014 Sep 19.
Published in final edited form as: Cochrane Database Syst Rev. 2010 Jan 20;(1):CD006625. doi: 10.1002/14651858.CD006625.pub2

Comparison 7. QUETIAPINE versus RISPERIDONE- sensitivity analysis (skewed data excluded).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mental state: 6. Positive symptoms - average endpoint score - (PANSS positive subscore, high=poor) 6 1225 Mean Difference (IV, Random, 95% CI) 1.76 [1.04, 2.48]
 1.1 short term 3 998 Mean Difference (IV, Random, 95% CI) 2.08 [0.60, 3.56]
 1.2 medium term 2 146 Mean Difference (IV, Random, 95% CI) 2.15 [−0.01, 4.31]
 1.3 long term 1 81 Mean Difference (IV, Random, 95% CI) 1.30 [−0.13, 2.73]
2 Adverse effects: 1. Extrapyramidal effects -Simpson-Angus Scale (high= poor) 4 1033 Mean Difference (IV, Random, 95% CI) −0.82 [−1.95, 0.31]