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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: J Comp Neurol. 2014 Jul 30;522(17):3861–3884. doi: 10.1002/cne.23646

Figure 8.

Figure 8

Direct effects of LTP on nascent zones. (A) The summed NZ area per synapse was correlated with PSD area but did not change following TBS at 5 min (control, r = 0.69, p < 0.0001; LTP, r = 0.73, p < 0.0001; ANCOVA, F(1,125) = 0.28, p = 0.60) or (B) at 30 min (control, r = 0.72, p < 0.0001; LTP, r = 0.52, p < 0.0001; ANCOVA, F(1,241) = 7.4, p < 0.01). (C) Summed NZ area remained well-correlated with PSD area in the 2 hr condition, and increased significantly during LTP (control, r = 0.49, p < 0.0001; LTP, r = 0.65, p < 0.0001; ANCOVA, F(1,195) = 11.4, p < 0.001). For PSD areas ≥ 0.4 μm2 and NZ areas ≥ 0.1 μm2 the following points are plotted: 5 min LTP (0.61 μm2, 0.069 μm2), 30 min control (0.43 μm2, 0.065 μm2; 0.61 μm2, 0.085 μm2), 30 min LTP (0.54 μm2, 0.054 μm2), and 2 hr LTP (0.34 μm2, 0.12 μm2; 0.66 μm2, 0.089 μm2; 0.62 μm2, 0.050 μm2).