Table 2.
Sample of dense core vesicles and docked vesicles.
| Condition | Description | # DCV/Bouton | # docked vesicles |
|---|---|---|---|
| Perfusion-fixed | N | 37 | 124 |
| mean ± SD | 2.1 ± 1.4 | 6.2 ± 4.8 | |
| maximum | 6 | 24 | |
| 5 min control | N | 51 | 189 |
| mean ± SD | 1.9 ± 1.2 | 15 ± 10 | |
| maximum | 7 | 75 | |
| 5 min LTP | N | 39 | 145 |
| mean ± SD | 1.8 ± 1.1 | 16 ± 12 | |
| maximum | 5 | 62 | |
| 30 min control | N | 69 | 201 |
| mean ± SD | 1.9 ± 1.4 | 7.4 ± 7.2 | |
| maximum | 8 | 41 | |
| 30 min LTP | N | 81 | 236 |
| mean ± SD | 1.7 ± 1.2 | 5.8 ± 5.2* | |
| maximum | 7 | 31 | |
| 2 hr control | N | 35 | 152 |
| mean ± SD | 1.66 ± 0.97 | 10.5 ± 8.8 | |
| maximum | 4 | 54 | |
| 2 hr LTP | N | 62 | 245 |
| mean ± SD | 1.4 ± 1.0 | 11.3 ± 10.8 | |
| maximum | 8 | 69 |
N = the number of boutons analyzed for percentage of boutons with DCVs and the number of docked vesicles per bouton. The mean ± standard deviation (SD) and ranges are provided for the number of DCVs per bouton (including only boutons that had at least 1 DCV) for the number of docked vesicles per synapse. Statistical comparisons of LTP versus time-locked controls: for number of DCVs per bouton (main effects ANOVAs: 5 min, F(1,85) = 0.15, p = 0.70; 30 min, F(1,146) = 0.63, p = 0.43; 2 hr, F(1,94) = 1.2, p = 0.28) and for docked vesicles per synapse (hnANOVAs, 5 min, F(1,313) = 0.33, p = 0.57; 30 min, F(1,401) = 4.6, p = 0.032*; 2 hr, F(1,377) = 0.028, p= 0.87).