Figure 3. Sample images of activated HUVEC monolayers exposed to PLGA in different flow mediums.

Phase image of 1.4 µm sLea-coated PLGA spheres bound to IL1-β-activated HUVEC monolayer after 5 min of flow of particles in (A) RBC-in-Buffer, (B) whole blood, and (C) plasma at 200 s−1. Image taken at 20× magnification. sLea density = 1500+/−100 sites/µm2 (SEM). Particle concentration = 5e5 particles/mL. Scale bar = 20 µm